AFI48-110 governs the Military Vaccination Program, including immunization standards, requirements, exemptions, records, and chemoprophylaxis.
View AFI48-110 on armypubs.army.mil
AFI48-110 addresses personnel subject to immunization, specific vaccine requirements, biological warfare defense, and investigational or emergency-use products. It requires screening for contraindications, completion of immunization series, and documentation of immunizations and exemptions.
The Military Service policy concerning immunizations follows the recommendations of the CDC and the Advisory Committee on Immunization Practices (ACIP) and the prescribing information on the manufacturer’s package inserts, unless there is a military-relevant reason to do otherwise. (paragraph 2–1)
Any vaccine or drug licensed by the U.S. Food and Drug Administration (FDA) or the U.S. Department of Health and Human Services (DHHS) may be used, as well as vaccines or drugs compliant with applicable DOD investigational new drug (IND) or emergency use authorization (EUA) processes. (paragraph 2–1)
Restarting an immunization series or adding extra doses is not necessary when an initial series of a vaccine or toxoid is interrupted; instead, give delayed doses as soon as feasible. (paragraph 2–1)
Doses in an initial series administered 5 or more days earlier than the minimum interval should not be counted as valid doses. (paragraph 2–1)
Screen all potential vaccines for contraindications, precautions, or warnings per the prescribing information on the manufacturer’s package insert. (paragraph 2–1)